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The -SH group acts as an effective electron donor and acceptor for many biological reactions (Xiang et al

81627901), the National Natural Science Foundation of China (Grant Nos

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3 Metabolic reprogramming related to ferroptosis in OA Having established the significance of ferroptosis in OA pathology, we now turn our attention to how metabolic reprogramming involving lipids, amino acids, iron, and glucose underpins ferroptotic susceptibility

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For example, glutathione can easily attach and detach from other glutathione molecules and other proteins that have this functional group