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Sleep Disruption Irritability Worsening Behavior Aggression These side effects often improve with dosage adjustments or timing changes

doi: 10.1007/s13204-022-02638-9 314 ZhangW.LiuQ

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Nicotinamide N-methyltransferase (NNMT) is an enzyme that methylates nicotinamide using SAM as a methyl donor