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Sfholm J, Abma W, Bankova LG, Boyce JA, Al-Ameri M, Orre AC, et al

Oxidative stress induces the dissociation of the NRF2-Keap1 complex When cells undergo oxidative stress, ionizing radiation, or chemical stimulation, it may lead to the generation of reactive oxygen species (ROS) or reactive oxygen free radicals within the cells, triggering an oxidative stress response

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According to the bias assessment using the Cochrane Collaborations risk of bias tool, this study had a lower risk of bias

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We discovered that ROS increase in host cells during infection, and these ROS are likely generated by the host rather than from the pathogen itself