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A.TuckerS.GhofraniJ.et al (2016)

reactive proteostasis: a functional continuum Rather than acting as isolated modules, proteostasis pathways operate along a functional continuum that spans proactive maintenance and reactive stress responses

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The inhibitor of B kinase (IKK) phosphorylates IB twice in a single binding event through a sequential mechanism

Because the liver is either a source or sink for accumulation of heme precursors, or porphyrins, we investigated the role of Wnt/beta-catenin signaling, a pathway that contributes to unique hepatic attributes such as zonation, autophagy, and metabolic regulation