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As the initiation site of ferroptosis, the atrophy of cell mitochondria morphology and the decline of mitochondrial membrane potential after DON treatment provide important evidence for us to judge the occurrence of ferroptosis 50

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a , Body weight of Control, Bmal1 -KO, and Bmal1 -KO + NDI1 mice at 4 months of age on a chow diet (n = 7 Control, n = 6 Bmal1 -KO, and n = 5 Bmal1 -KO + NDI1)

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Journal of Orthopaedic Research , 28(9), 1155-1161

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