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(Oxf.) (2013) 79:438

In mouse models, the team introduced combined therapy including PD-L1 blocker and cyst(e) inase (a bioengineered enzyme that degrades cystine and cysteine) and such treatment can enhance the efficacy of CTL-mediated anticancer effects, supporting the idea that inducing ferroptosis could be considered a productive way for treating cancer and overcoming immunotherapy resistance (Wang et al., 2019)

The homeoprotein Nanog is required for maintenance of pluripotency in mouse epiblast and ES cells

Given the serious impact of chemotherapy side effects, there is an urgent need for treatments that can protect healthy tissues without reducing the effectiveness of cancer treatments

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