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Pietzke, M., Meiser, J

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NAC supports healthy levels of glutathione by providing the body with cysteine, the rate-limiting factor (a factor that prevents the process from happening more quickly) of glutathione production thus, depleted cysteine can lead to depleted glutathione

Bentzley JP, Tomko RL, Gray KM

Moreover, in this study, the elevated pool of organic acids (TCA intermediates) and vitamins (including ascorbic acid and pantothenic acid) particularly in the stress + FFA treatment, suggests improved energy flux and vitamin cofactor availability, both of which are crucial for enzymatic steps in the ascorbateglutathione cycle [71]