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Promoter methylation and transgene copy numbers predict unstable protein production in recombinant Chinese hamster ovary cell lines

Buettner JM, Sowoidnich L, Gerstner F, Blanco-Redondo B, Hallermann S, Simon CM (2022) P53-dependent c-Fos expression is a marker but not executor for motor neuron death in spinal muscular atrophy mouse models