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Since APOE4 is the greatest genetic risk factor for late-onset AD, it would be interesting to perform a single-nucleus profiling analysis in APOE4 carriers to determine how this isoform impact the transcriptome of the various cell types, including microglia and astrocytes

Blum MR, Liao SH, Good SS, de Miranda P

However, there are case reports of hepatic fibrosis resulting in portal hypertension in patients with autosomal dominant polycystic kidney disease

Fibroblast ferroptosis is involved in periodontitis-induced tissue damage and bone loss

Seaweed polysaccharides treatment alleviates injury of inflammatory responses and gut barrier in LPS-induced mice

range 0.01830.435) are within the ranges reported in the literature for postmortem CNS concentrations of GSH in subjects with PD