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In addition, ROS may amplify the inflammation process of gene expression involved in the inflammatory response, particularly via

Determinants of outcome: where, when, how much Outcome is governed by three non-independent axeswhere, when and how much: where the ROS originate and in which compartment (e.g., NOX microdomains versus mitochondria and ER versus peroxisome) sets the immediate molecular targets and the surrounding antioxidant context that shapes reactivity (To et al

It layers well with basically everything: niacinamide, hyaluronic acid, peptides, and vitamin C, and also pairs nicely with stronger actives like retinoids and exfoliating acids where it can help take the edge off irritation

Schaffer SW, Shimada-Takaura K, Jong CJ, et al

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