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[5] Mechanistic data indicate PAT inhibits NF-B nuclear translocation, the transcription factor governing proinflammatory cytokine and COX-2 gene expression

The meta-analysis, which pooled data across multiple studies using a random-effects model, found that lower B12 was significantly associated with metabolic syndrome markers including elevated blood pressure, elevated fasting glucose, and abnormal lipid profiles

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However, as with many experimental compounds, its unregulated nature makes it high-risk for athletes