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However, to ensure their safe, effective, and scientifically guided use, attention must be given to dosage control and population-specific suitability during further development and clinical application

Villalba, J

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943 NG/EDA is triggered by the acidic and edaravone-induced high levels of GSH microenvironment, enabling selective and sustained release of edaravone at the site of ischemic injury to enhance its neuroprotective effects

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doi: 10.1016/S0736-4679(01)00324-9