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230,250 For example, celecoxib, a non-steroidal anti-inflammatory drug, targets the cyclooxygenase 2 (COX-2)/AKT pathway and was sufficient to inhibit the progress of HCC by inhibiting lipogenesis

Darinaparsin belongs to the class of organic arsenical compounds that are generally considered less toxic than inorganic ones (Waxman and Anderson, 2001

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Once released into the extracellular space, especially after tissue injury, they undergo changes from reducing to oxidizing environments that alter their function, associated with mitochondrial dysfunctions