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In terms of antioxidant effects, flavonoids activate the Nrf2/antioxidant response element (ARE) pathway, upregulating the expression and activity of antioxidant substances such as heme oxygenase-1 (HO-1), superoxide dismutase (SOD), catalase (CAT), and glutathione (GSH), while reducing the levels of malondialdehyde (MDA), lipid peroxides (LPO), and excess nitric oxide (NO), thereby alleviating intestinal oxidative damage (Lyu et al., 2022

The study, which was recently published in the scientific journal "Antioxidants", reported that a single dose of liposomal glutathione could increase glutathione (GSH) levels in whole blood over a period of 10 hours and maintain these increases for at least a further 14 hours

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Biomedical applications RSSP in RBCs The protocol described in this manuscript for the detection of GSSP in RBCs as biomarkers of oxidative stress was applied in our laboratory to human and rat samples

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10.1038/s41467-019-13419-4 33 NigroC.LeoneA.RacitiG