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Additionally, it influences the phosphatidylinositol-3-kinase (PI3K)/protein kinase B (AKT) and mitogen-activated protein kinase (MAPK) pathways, both of which play critical roles in cell survival and apoptosis regulation (217)

[DOI] [PubMed] [Google Scholar] Bayer ML, Yeung CYC, Kadler KE, Qvortrup K, Baar K, Svensson RB, Magnusson SP, Krogsgaard M, Koch M, Kjaer M (2010) The initiation of embryonic-like collagen fibrillogenesis by adult human tendon fibroblasts when cultured under tension

Raju P, Shashikanth N, Tsai PY, Pongkorpsakol P, Chanez-Paredes S, Steinhagen PR, et al

Results showed that glutathione increased bone density in the mice despite the estrogen lack

Further, mitophagy was proposed as a specific therapeutic target to advance treatments of ischemic stroke [540]

Ursolic acid regulates key EMT transcription factors, induces cell cycle arrest and apoptosis in MDA-MB-231 and MCF-7 breast cancer cells, an in-vitro and in silico studies