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It plays a key role in cellular detoxification, immune function, and protection against oxidative stress, helping maintain overall health

Therapeutic interventions aimed at modulating lipid availability, such as ACAT inhibitors, PPAR antagonists, or scavenger-receptor blockade, can reduce the supply of anti-ferroptotic lipid mediators and promote oxidative lipid stress within tumor cells

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Decide what you will do instead of what you will try to get children to do

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In addition, GPX4 expression in IECs of patients with IBD is crucial for maintaining intestinal homeostasis [66], and activation of GPX4 can significantly reduce IECs ferroptosis and improve IBD symptoms [62]