Moreover, they found that specific tocotrienols increase ERb translocation into the nucleus which, in turn, activates the expression of estrogen responsive genes (MIC-1, EGR-1 and Cathepsin D) in breast cancer cells only expressing ERb cells (MDA-MB- 231) and in cells expressing both ER isoforms (MCF-7)
however the mechanism for these actions is still unclear

DLB Dementia with Lewy Bodies DT Dihydrotanshinone I ether-PL ether-Phospholipid EVNs Extracellular Vesicle-Based Nanoformulations FASN Fatty Acid Synthase FGF Fibroblast Growth Factor FOXD3 Forkhead Box D3 FPN Ferroportin FSP1 Ferroptosis Suppressor Protein 1 FTH1 Ferritin Heavy Chain 1 GA Granulathiazole A GCH1 GTP Cyclohydrolase 1 GPX4 Glutathione Peroxidase 4 GR Glutathione Reductase GS Glutathione Synthetase GSH Glutathione GSSG Oxidized Glutathione GWAS Genome-Wide Association Studies HMOX1 Heme Oxygenase 1 HO-1 Heme Oxygenase 1 HSPB1-Heat Shock Protein Beta-1 IFN- Interferon-gamma IPMDS International Parkinson and Movement Disorders Society IRE Iron-Responsive Element IRP1 Iron Regulatory Protein 1 IRP2 Iron Regulatory Protein 2 LBs Lewy Bodies LEV Levetiracetam LOX Lipoxygenase LPCAT3 Lysophosphatidylcholine Acyltransferase 3 LPS Lipopolysaccharide LRP1 Low-density Lipoprotein Receptor-related Protein 1 LRRK2 Leucine-Rich Repeat Kinase 2 MAO Monoamine Oxidase MDA Malondialdehyde MPO Myeloperoxidase MPP + 1-Methyl-4-phenylpyridinium MPTP 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine MSA Multiple System Atrophy MT1 Melatonin Receptor 1A MTs Metallothioneins NAC N-Acetylcysteine NCOA4 Nuclear Receptor Coactivator 4 NO Nitric Oxide NOX2 NADPH Oxidase 2 Nrf2 Nuclear Factor Erythroid 2-Related Factor 2 ONE 4-oxo-2-nonenal OPG Osteoprotegerin OPN Osteopontin p53 Tumor Protein p53 PD Parkinsons Disease PDD Parkinsons Disease Dementia PE Physical Exercise PINK1 PTEN-induced putative kinase 1 PLP Pyridoxal Phosphate PL-PUFAs Phospholipid-Polyunsaturated Fatty Acids PQS Pseudomonas Quinolone Signal PRKN Parkin RBR E3 Ubiquitin-Protein Ligase PUFAs Polyunsaturated Fatty Acids PV-INs Parvalbumin-Positive Interneurons QSM Quantitative Susceptibility Mapping Que
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In our study, we showed the opposite connection: exogenous GSH increased H 2 S level (Figure 3D) that also had an antioxidative effect manifested in the reduction of oxidative stress markers in the heart mitochondria of old rats (Table 2)
Nhc im: - thy r hiu qu, sn phm ny c th cn c s dng thng xuyn v trong thi gian di
doi: 10.1038/s12276-023-00965-7 16 ZhangQRaoofMChenYSumiYSursalTJungerWet al