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The primary bactericidal role of neutrophils is accomplished via phagocytosis and the creation of neutrophil extracellular traps (NETs), which are composed of degraded chromatin and granular proteins from within the cell, triggered by various stimuli

Furthermore, inhibiting the kynurenine (KYN) pathway synergized with anti-PD-1 therapy to achieve robust tumour eradication in adipose-rich tumour models

U.KogerS.SharmaS.Sener-AydemirA.RuczizkaU.KreutzmannH.et al (2022)

However, the reviewed studies exhibit critical limitations that significantly impair their clinical impact

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