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Science 369 , 14811489 (2020)

Recent studies have identified that the mitochondrial AAA protease Lon interacts with multiple protein partners to promote the generation of ROS, which in turn activates the NF-B signaling axis, amplifying downstream oncogenic pathways and contributing to tumor development and immune evasion [58]

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Ketorolac-induced platelet dysfunction may lead to prolonged bleeding time, purpura, and anemia, all of which have been reported in 1% to 10% of patients taking ketorolac or another NSAID during clinical trials

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Cerebral MRI in one subject showed, aside from bilateral optic nerve atrophy, scattered white matter alterations