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Mechanisms of apoptosis induction by BH3 inhibitor ABT-737 in AML

In rabbits fed a 0.5% high-cholesterol diet, VEGF receptor-2 decreased in the CC, while VEGF increased initially but declined later [132], another study by Ryu et al also showed that in rats on a 4% high-cholesterol diet for 3 months, VEGF and VEGF receptor-2 were downregulated in the CC [133]