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Combining this with mBBr staining that measures intracellular GSH content (Figure 5I), the ratio of BODIPY-PE hi mBBr hi to BODIPY-PE lo mBBr lo could thus be potentially indicative of the capacity of activated cells to maintain resistance to ferroptosis

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Patients and Methods Ethics Statement This study was approved by the Ethics in Research Committee at the Federal University of Gois under protocol number 195/11 dated 27 th June, 2011 and was conducted according to the Ethical Principles for Medical Research Involving Human Subjects of the World Medical Association Declaration of Helsinki