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FOXO4-DRI is a senolytic peptide engineered to selectively destroy senescent cells the damaged, non-dividing cells that accumulate with age and drive chronic inflammation, tissue dysfunction, and frailty

Furthermore, UGTs are involved in the regulation of several active endogenous compounds such as bile acids or hydroxysteroids due to their inactivation via glucuronidation (Miners & McMackenzie, 1991, Kiang et al., 2005)

doi: 10.1073/pnas.1009427107 38 ItohNNakayamaYKonishiM

Regulatory T cells protect from local and systemic bone destruction in arthritis

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Zhang W, Zhao L, Zhang J, Li P, Lv Z