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[DOI] [PMC free article] [PubMed] [Google Scholar] 121

The rationale for N-acetylation stems from established peptide chemistry principles

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Enrico Costa, of the Italian Medicines Agency (AIFA) and the Program On Regulation, Therapeutics, And Law (PORTAL) at Brigham and Womens Hospital and Harvard Medical School, and colleagues said FDA licensed nearly all approved products with an orphan drug designation between 2011 and 2020