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It is the gold-standard antidote for acetaminophen-induced liver failure , used in hospitals worldwide with a decades-long safety record

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Clin Trans Sci (2021) 14(4):1390402

Tumor cells, indeed, have shown higher levels of GSH than normal cells and often are characterized by an overexpression of GSH-related enzymes and proteins that lead to a better resistance to antineoplastic treatments and, possibly, could favor chemoresistance [116,117,118]

The function of GSH in hepatocytes has been investigated by pharmacological inhibition or genetic ablation of the glutamate-cysteine ligase (GCL), the rate-limiting and regulatory enzyme in GSH biosynthesis

(5) Other functions of glutathione include helping the liver deal with fats, assisting regular cell death, and helping certain enzymes to function