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Description

The p53(3KR) mutant, lacking acetylation due to lysine-to-arginine substitutions at three residues, decreases expression of SLC7A11 without affecting other p53 targets such as CDKN1A/p21 (involved in cell cycle progression) or BAX (involved in apoptosis)

Pathways that were significantly altered in schizophrenia were related to environmental information processes such as saccharide, polio, and lipid transport systems

J Pharmacol Exp Ther 329:10231031

These cell lines were maintained in Dulbeccos Modified Eagles Medium (DMEM) (Thermo Scientific, #12100061)low glucose for HepG2 (Thermo Scientific, #31600091), supplemented with 1 % Penicillin/Streptomycin (P/S) and 10 % Fetal bovine serum (FBS) (Natocor)