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Studies on MTHFR variants show no interactions with vaccinations, with the exception of a smallpox vaccine that is not regularly given

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Although a fairly large proportion of patients have reported a number of side effects, particularly at the gastrointestinal level (nausea, vomiting, diarrhoea), these side effects tend to diminish over time and adherence to treatment remains high, with about 5% of patients discontinuing treatment due to side effects

The FDA has given compounding pharmacies and facilities a deadline of April 22, 2025, or May 22, 2025 (depending on the type of compounding pharmacy or facility) to stop offering compounded semaglutide