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10.1007/s00232-021-00189-8 5 AkbaraliH

422 Two large cross-sectional studies using detailed QST profiling found greater thermal insensitivity in painful than painless DPN, suggesting more advanced small fiber dysfunction

No, it is not a traditional weight loss drug

The increase in lactate that we detected points towards a defect in oxidative energy metabolism, but this conclusion must be treated cautiously given the difficulty of measuring lactate in the presence of the much larger and broader macromolecule (MM) resonance at ~1.35 ppm, with the lactate signal being a small shoulder on that peak (Fig