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Fller M, Sopjani M, Koka S, Gu S, Mahmud H, Wang K, et al

Zhou et al., 2013)

Quantitative assessment of primary skin irritants in vitro in a cytotoxicity model: comparison with in vivo human irritation tests

Hormone Res (1993) 40:1622

Class 3 represents a more complex picture: patients who sleep long yet poorly, shaped by psychological distress, neurocognitive disturbances (vivid dreaming as a marker of REM dysregulation), and iatrogenic factors (glucocorticoids, hypnotics)