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VPS33B regulates protein sorting into and maturation of -granule progenitor organelles in mouse megakaryocytes

Although a number of pre-clinical phage display studies show promise for the utility of cancer-targeting peptides [16, 17], clinical data demonstrate the need for further optimisation for translational success in terms of improving receptor affinity, enzyme instability and pharmacokinetics [18, 19]

Finally, oxidative stress itself can promote non-enzymatic synthesis of KYNA from KYN or indole-3-pyruvic acid, independent of KAT activity [169]

Wang X, Sun X, Bu T, Wang Q, Jia P, Dong M, Wang L