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Interestingly, one clinical report has demonstrated that patients with CRT deficiency exhibit increased GAA levels, as well as the absence of CT in the brain [75], implying a causal relationship between the gene defect of CRT and the increase in brain GAA level

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[DOI] [PMC free article] [PubMed] [Google Scholar] 116.Myint Z.W., Sun R.C., Hensley P.J., James A.C., Wang P., Strup S.E., McDonald R.J., Yan D., St Clair W.H., Allison D.B

Effect of insulin on glucose- and arginine-stimulated somatostatin secretion from the isolated perfused rat pancreas

Meanwhile, the expression of Sirt3, NAD+, and NAMPT were reduced in the KLF4-deficient heart, all of which decreased deacetylase activity in the mitochondria

Soils are also one of the potential carbon pools that could significantly help decrease greenhouse gas (GHG) emissions in the atmosphere