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Visualization was contributed by SZ, XM, SS, BD, AO, and KWS

Stelmaszynska, T., Kukovetz, E., Egger, G., and Schaur, R

We evaluate how supplementation can augment molecules in the NAD pathway

Within endosomal vesicles, Fe 3+ undergoes six-transmembrane epithelial antigen of prostate 3 (STEAP3)-catalyzed reduction to Fe 2+ , subsequently exported to cytosol via divalent metal transporter 1 (DMT1) ( 2+ complexes are sequestered in the labile iron pool (LIP) through ferritin binding