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Nrf2 translocation was assessed by quantification of the mean GFP intensity in the nucleus over time

Hair follicles cycle between growth (anagen), transition (catagen), and rest (telogen) phases

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It is found widely in nature and is involved in numerous enzymatic reactions in which it serves as an electron carrier by being alternately oxidized (NAD+) and reduced (NADH)

This pharmacokinetic profile is fundamentally different from oral supplements, which reach peak plasma concentration 6090 minutes after ingestion and clear within 68 hours