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Rats received bilateral icv injections of artificial cerebrospinal fluid (SHAM) or STZ (STZ and STZ+FTS groups) (3 mg/kg)

Przejcie od bada na zwierztach do tych na ludziach - a nastpnie uzyskanie penej licencji na lek - zajmuje lata i kosztuje miliardy dolarw

Science 287 , 10111013 (2000)

Occludin S408 phosphorylation regulates tight junction protein interactions and barrier function

The now days mostly used standardized CPZ mice model was first established in 1998 by the Matsushima group (Hiremath et al., 1998)

Fragment 176-191 has been heavily researched in animal models because even while it preserves the fat-burning effects of hGH, it avoids some other effects of its parent protein such as increasing insulin-like growth factor-1 (IGF-1) levels, negatively impacting carbohydrate metabolism, altering insulin sensitivity, increasing long bone growth, and so forth