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Another human sleep-wake study reported improved daytime alertness or performance, but sample size was not clearly reported and it was not an exercise-recovery trial [6]

For instance, in AD mice, mitochondrial damage increases mtDNA leakage into the cytosol, where it engages cGAS and activates STING, driving microglial secretion of type I interferons and pro-inflammatory cytokines that contribute to neuronal dysfunction [93]

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the existing pre-clinical protocols use either injections or topical administration of the compound