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Ficz G, Gribben JG

This study will evaluate the safety and feasibility of dentate nucleus stimulation in conjunction with physical therapy in patients with moderate to severe upper-extremity hemiparesis following middle cerebral artery ischemia

45,46 As shown in Figure 2 , GLP-1RAs penetrate the blood-brain barrier and directly activate GLP-1 receptors in the hypothalamus, especially within the ARH nucleus, a key center for appetite regulation