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To further understand the impact of acidic pH on the expression of genes involved in transsulfuration ( metB and metC ) and direct sulfhydrylation ( metZ ), we quantified their expression in M

Both events would lead to elevated levels of active Nrf2 and Nrf2 nuclear accumulation

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Oncogene 2012;31:186983

Hendrikx JJ, Lagas JS, Rosing H, Schellens JH, Beijnen JH, Schinkel AH