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doi: 10.3390/nu9040341

Cyanocobalamin is a synthetic form of vitamin B12 that is commonly used in supplements and B12 shots

P., Lesage, S., Dean, T

Gao J, Katagiri H, Ishigaki Y, Yamada T, Ogihara T, Imai J, et al

Considered together, these 3 studies suggest that the effect of metformin on circulating vitamin B-12 concentrations is not sufficient to have a significant effect on functional vitamin B-12 status, as indicated by methylmalonic acid