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As absorption is reduced, body stores become low and a deficiency occurs Underlying diseases most commonly include: IBD (inflammatory bowel disease) Intestinal cancer (especially small cell lymphoma) Liver disease Pancreatitis and other pancreatic diseases Symptoms of low B12 levels Typically found in middle-aged or older cats that present with: Weight loss Diarrhea Vomiting Anorexia Thickened intestines In humans, B12 deficiency may also be associated with dementia, cardiovascular disease, and a certain type of anemia, although these are not specifically recognized problems in cats

These findings provide additional evidence supporting the hypothesis

10.1158/1078-0432.CCR-12-1424 72 NotoJ

Yang F, Wang Y, Nowakowski GS, Wang M , Chintakuntlawar AV, Halfdanarson TR, Pagliaro LC, Wei J, Liu B, Molina JR, Markovic S

doi:10.1089/acm.2011.0531 Poloni MM, Marques NP, Ribeiro Junior NV, Sperandio FF, Hanemann JAC, de Carli ML

Y., & Lee, M.-S