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TGF- pathway Ionizing radiation-induced ROS activate latent TGF-1 by oxidizing Met253 in its LAP, triggering conformational changes, suggesting the isoform specificity of ROS in TGF- activation

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Moreover, for patients with renal and liver failure, anorexia and restriction of foods rich in protein, potassium, and phosphate contribute to decreased folate intake

Our hypothesis is that when grown in coculture with SDFT tenocytes, licensed MSCs will enhance parameters of tenocyte function beneficial to the healing tendon compared to nave MSCs