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The brain and both kidney and intestinal tissues exhibit high levels of ASCT2 expression because they require large amounts of glutamine

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Around 30% of patients start with bulbar symptoms, which affect the muscles used for speaking and swallowing, leading to problems like slurred speech (dysarthria), trouble swallowing (dysphagia), and twitching of the tongue muscles (Chi et al., 2013)

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Oner of the problems in the clinical use of NBDHEX may arise from its lack of specificity for GSTP1-1