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Its a cornerstone of many projects within our Mitochondrial Research community

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Here are some of the potential side effects of glutathione in case of a dose larger than 5 grams: Weight gain Nausea Skin rashes, hives, or allergic reactions Eye disorders Diarrhoea Pain/Numbness Aggravated Asthma Hair whitening or loss Liver, renal, and nerve system toxic effects

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doi: 10.3389/fimmu.2025.1722463 Received 10 October 2025 Revised 03 December 2025 Accepted 12 December 2025 Published 12 January 2026 Volume 16 - 2025 Edited by Gabriella dEttorre, Sapienza University of Rome, Italy Reviewed by Christina K

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Although this adaptation initially helps meet the hearts high energy demands, chronic reliance on FA oxidation results in lipotoxicity, mitochondrial stress, and eventually, impaired cardiac function

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