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doi: 10.1111/andr.12655 40 De RosaMZarrilliSPaesanoLCarboneUBoggiaBPetrettaMet al

Beyond energy production, NAD+ is also crucial for supporting DNA repair[1][2], regulating inflammation[2] and maintaining mitochondrial function[2]

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This area requires more attention in future research, especially in the context of 15-LOX activity and redox-regulation of signalling that controls 15-LOX-derived metabolite formation as there are some conflicting reports of the role of this pathway in disease progression