5-amino-1mq human studies safety Peptide Selective and membrane-permeable small molecule

The researchers grew mouse and human cells in the laboratory and treated them with AOD9604 to see how it changed the cells ability to burn fat

Notably, the enzyme has been linked to obesity and type 2 diabetes (T2D)

The enhanced cellular energy production translates to improved daily energy levels before any weight changes occur

Reactions were performed with 5 M histone H3 (histone L-arginine) substrate, 1 M radiolabeled S-adenosyl-L-[methyl- 3 H] methionine (SAM) co-substrate, and recombinant human PRMT3 enzyme

Research shows that NNMT inhibition promotes oxidative muscle fibers and preserves lean mass during weight loss

For researchers interested in body recomposition rather than just weight loss, these properties are particularly valuable