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For instance, intraventricular delivery of the iron chelator DFO led to an improvement in the motor phenotype of R6/2 HD mice (Skouta et al

Mitroshina EV, Savyuk MO, Ponimaskin E, Vedunova MV

Noteworthy, overlapping RNA and DNA signals over the Ubx WT monomer suggest that one Ubx molecule can contact RNA and DNA simultaneously

It was also observed that the expression of truncated sortilin and the small interfering RNA (siRNA)-mediated knockdown of sortilin in primary neurons resulted in the missorting of BDNF to the constitutive pathway, further supporting the finding that sortilin regulates the sorting of BDNF to the RSP [9]

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Kidney Int (2019) 95(4):88095