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Clinical laboratories generally define vitamin B12 deficiency as a serum level below 148 pmol/L (approximately 200 pg/mL)

Similarly, significantly increased IL-6 and LPS-binding protein levels were observed in US NS workers, indicating time-dependent immune activation 143

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These transcription factors are composed of three conserved functional domains, a DNA binding domain (DBD), a transcription activation domain (TAD) and an incompletely defined negative regulatory domain (NRD) (Thompson and Ramsay, 1995)

Methods: Data of patients hospitalized between 2012 and 2021 with at least one ICD-10 code of cirrhosis and / or HCC were extracted from the French national medicalized information system program