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Pre-clinical studies done on C57BL/6J mice using total body irradiation (9 Gy) found that radiation reduced -diversity of gut microbiota, while urolithin A (UroA), a gut microbial metabolite, helps in alleviating radiation-induced apoptosis in intestinal cells by suppressing P53 signaling pathway (Zhang et al., 2021c

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The cluster heatmap of all DEPs between the model and DP groups was generated using the heatmap.2 function of gplots

10.1021/acs.jmedchem.4c02927 59 JinY.ZhangC.XuH.XueS.WangY.HouY.et al (2011)

10.1104/pp.126.1.445 104 PrasadT