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Figure S4

An integrative metabolomics and network pharmacology method for exploring the effect and mechanism of Radix Bupleuri and Radix Paeoniae Alba on anti-depression

There is preclinical and animal data along with methodologically flawed studies

James SJ, Melnyk S, Jernigan S, Cleves MA, Halsted CH, Wong DH et al

In our study, we assumed that Al bio-exclusion could primary be the strategy to limit the intracellular migration of the metal into roots and thereby reducing phytotoxicity