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The decreased affinity of VpreB UR for both, the C H 1 domain and even more pronounced the V H domain, suggests that the UR of VpreB is a determining factor in HC interaction monitoring structural features of the HC

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In particular, the cation of the salt is an alkali metal or an alkaline earth metal, for instance Na + , K + , Li + , Cs + , Ca 2+ , or another metal, such as Zn 2+ , or a primary, secondary or tertiary amine or organic compound, such as NH 4 + , triethanolamine + , cyclohexylamine + , 2-AMP + (2-amino-1-propanol) or TRIS + (Tris-(hydroxymethyl)-aminomethan), as long as these cations are physiologically acceptable

However, its best to space them out by 3-4 hours for better absorption

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