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Conversely, M2 macrophages demonstrate diminished antigen-presenting capacity, releasing anti-inflammatory cytokines like interleukin (IL)-10 or TGF-, and suppressing immune responses [122]

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GSTM2 modulates growth of LDs via ASK1-p38/JNK signalling The growth of LDs is important in increasing the cellular capacity for lipid storage

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Additionally, using SIRT1 knockout mice and STAT3 knockout mouse models may provide more conclusive insights into GHKs mechanism of action

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