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Nrf2 and ferroptosis: A new research direction for neurodegenerative diseases

A plasma levels and deposition were found to be significantly reduced in APP/PS1 mice after 12 months of melatonin supplementation

Impaired Biosynthesis: Chronic hyperglycaemia suppresses GCLC and GSS, the two enzymes that synthesise new glutathione within cells

One hour after the sixth gavage, mice were euthanized by CO 2 asphyxiation and the small intestine and colon were collected

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